In this video, Dr Abhishek Shukla, Consultant Cardiologist at Ajanta Hospital, Lucknow, shares key insights from the COMBINE-Angina study – an international, prospective study evaluating the early addition of trimetazidine in patients with stable angina who remain symptomatic despite first-line hemodynamic therapy.
The study, published in the International Journal of Cardiology and presented at ESC Congress 2025, highlights the clinical value of combining metabolic and hemodynamic approaches in angina management.

Dr Shukla discusses the real-world relevance of SAQ-7 score improvements, the impact on patients’ daily lives, and the applicability of these findings in Indian clinical practice. He also shares practical takeaways for cardiologists managing symptomatic stable angina.

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