An experimental vaccine kept melanoma from returning or spreading in people at high risk of the skin cancer recurring, drugmakers Moderna and Merck announced Wednesday.

Type 2 diabetes has traditionally been a disease that has affected mostly middle-aged and older adults. But new research from the U.S. to be presented at the Annual Meeting of the European Association for the Study of Diabetes (EASD) in Milan, Italy (Sept. 28–Oct. 2) shows a sharp increase in the rate of new cases of type 2 diabetes since the turn of the century, which has continued to accelerate in recent years. The study is by Dr. Tessa Crume of the Colorado School of Public Health in Aurora, Colorado, and colleagues.

Each person has a unique gut microbial population, with variation shaped by diet, lifestyle and disease. We are seeing a rapid rise in metabolic disorders, obesity and inflammatory diseases that cannot be explained by our relatively stable genetic code. One of the most encouraging findings in common modern diseases is that modifiable factors can outweigh genetic predispositions. Unlike genetics, the microbiome is a dynamic system that responds to the daily choices we make.

Teenagers who are subjected to online bullying are at greater risk of later emotional and behavioral difficulties, research suggests.

For people living with diabetes, managing blood sugar can mean constantly watching the clock, keeping meals and medications on schedule and staying alert to changes in glucose levels. While little can be done about timed meals, researchers have developed a biological system that detects rising blood sugar levels and automatically responds by releasing medication to bring glucose back down.

Spinach, almonds and sweet potatoes are celebrated as some of the healthiest foods on the planet. But for the millions of Americans living with inflammatory bowel disease (IBD), a new study from the UNC School of Medicine suggests that these same foods may be quietly worsening gut inflammation through a compound most people have never heard of.

Imagine the body’s immune cells as a neighborhood cleanup crew. When all is healthy, macrophages roam tissues, clearing away cellular debris and helping maintain order. But obesity can turn these normally protective cells into drivers of chronic inflammation and metabolic disease.

A fifth death connected to West Nile virus was registered Saturday in North Macedonia, which is conducting extensive fumigation against mosquitoes, the country’s health authorities said.

Fire and medical officials have issued warnings about a supplement offered to Western wildland firefighters who have been exposed to toxic chemicals while battling some of the country’s biggest blazes.

Automatic crash notification (ACN) systems should become a standard safety feature in every new vehicle, like seat belts and airbags, according to a new paper by members of the American College of Surgeons Committee on Trauma (ACS COT), published in the Journal of the American College of Surgeons (JACS). The authors note that ACN is often offered as a premium connected-vehicle service that may stop working when a subscription expires.

Cottage cheese is having a moment. It’s being added to dips, mixed into batters and even used in pizza and brownies. It’s touted as a high-protein food that can help people build muscle and lose fat. But the research supporting these benefits is not quite as abundant as the number of viral cottage cheese recipes out there.

Climate variability in the Atlantic Ocean can help predict cutaneous leishmaniasis outbreaks in North Africa several months in advance. This is the finding of a new study led by the Barcelona Institute for Global Health (ISGlobal), together with researchers from the Pasteur Institutes of Tunisia, Morocco and France.

Researchers from the University of California San Diego and collaborators have identified a previously overlooked pattern of DNA mutations in colorectal cancer. Scientists use these patterns, known as mutational signatures, to investigate the biological and environmental processes that have damaged DNA during cancer development.

Crimean-Congo hemorrhagic fever virus (CCHFV) is a dangerous virus spread by ticks. It transmits Crimean-Congo hemorrhagic fever (CCHF), a serious disease that has been spreading into new regions worldwide. Capable of killing up to 40% of people infected, it currently has no widely approved, highly effective treatments or vaccines.

Deep brain stimulation, or DBS, may help improve speech and swallowing problems caused by traumatic brain injury (TBI), according to a new University of Pittsburgh School of Medicine study published in Nature Communications.

Researchers at the Fralin Biomedical Research Institute at VTC have developed an experimental oral therapy that protected mice from otherwise harmful radiation exposure while preserving radiation’s ability to destroy cancer cells, a finding that could ultimately improve cancer treatment and strengthen preparedness for radiological emergencies.

Hand grip strength. Balance tests. Standing up from a seated position on the floor. These physical challenges are often touted as measurements of healthy aging and even predictors of longevity.

Researchers at the Institute of Oceanology of the Chinese Academy of Sciences (IOCAS) have shown how a metabolic mechanism underlying thermal tolerance in intertidal oysters sheds light on malignant proliferation in human lung adenocarcinoma.

A first-in-class therapy to target MYC, one of the most sought-after and difficult targets in cancer biology, showed promise in hard-to-treat blood cancers, according to a new preclinical study from The University of Texas MD Anderson Cancer Center published in Blood.

For more than three decades, scientists have sought to combat diseases caused by protein misfolding by targeting the large protein clumps that accumulate in affected tissues. Yet, despite intensive efforts, clinical success has been limited.