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Good morning. Did Pfizer overpay for the obesity biotech Metsera? It’s probably still too early to tell, but we have some new data this morning.

The need-to-know this morning

Pfizer reported weight-loss results for a monthly GLP-1 obesity injection that it acquired as part of the $10 billion Metsera transaction. The pharma giant also reported fourth-quarter and 2025 earnings.

Merck’s earnings report can be found here. 2026 guidance was slightly below Street consensus.

FDA wants long-term monitoring of autoimmune patients receiving CAR-T

The FDA is advising drug developers to study the long-term effects of using CAR-T to treat patients with autoimmune conditions, out of concern the therapies could cause cancer or fertility issues.Continue to STAT+ to read the full story…

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