Regulators are trying to push drug development into a post-animal testing era. Meanwhile, a Jennifer Doudna-founded company is edging toward successful CAR-T therapy done in vivo, and a “triple-G” drug from Eli Lilly delivers strong results.

Lastly, don’t forget that today is STAT’s Breakthrough Summit East! Virtual tickets still available.

In-vivo CAR-T inches toward clinical reality

A new Nature paper from Azalea Therapeutics, a spinout of Jennifer Doudna’s lab, offers an early but notable step toward in vivo CAR-T — engineering cancer-fighting T cells directly inside the body rather than through the laborious lab-driven process.Continue to STAT+ to read the full story…

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